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Bayesian Forecasting Utilizing Bleeding Information to Support Dose Individualization of Factor VIII
Bayesian forecasting for dose individualization of prophylactic factor VIII replacement therapy using pharmacokinetic samples is challenged by large interindividual variability in the bleeding risk. A pharmacokinetic‐repeated time‐to‐event model‐based forecasting approach was developed to contrast t...
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| Udgivet i: | CPT Pharmacometrics Syst Pharmacol |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley and Sons Inc.
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6930854/ https://ncbi.nlm.nih.gov/pubmed/31668021 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12464 |
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