Mechanism of dorsal root ganglion stimulation for pain relief in painful diabetic polyneuropathy is not dependent on GABA release in the dorsal horn of the spinal cord

AIMS: It is hypothesized that dorsal root ganglion stimulation (DRGS), sharing some of the mechanisms of traditional spinal cord stimulation (SCS) of the dorsal columns, induces γ‐aminobutyric acid (GABA) release from interneurons in the spinal dorsal horn. METHODS: We used quantitative immunohistoc...

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Publicat a:CNS Neurosci Ther
Autors principals: Koetsier, Eva, Franken, Glenn, Debets, Jacques, Heijmans, Lonne, van Kuijk, Sander M.J., Linderoth, Bengt, Joosten, Elbert A., Maino, Paolo
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6930820/
https://ncbi.nlm.nih.gov/pubmed/31334605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.13192
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