Mechanism of dorsal root ganglion stimulation for pain relief in painful diabetic polyneuropathy is not dependent on GABA release in the dorsal horn of the spinal cord

AIMS: It is hypothesized that dorsal root ganglion stimulation (DRGS), sharing some of the mechanisms of traditional spinal cord stimulation (SCS) of the dorsal columns, induces γ‐aminobutyric acid (GABA) release from interneurons in the spinal dorsal horn. METHODS: We used quantitative immunohistoc...

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Detalhes bibliográficos
Publicado no:CNS Neurosci Ther
Main Authors: Koetsier, Eva, Franken, Glenn, Debets, Jacques, Heijmans, Lonne, van Kuijk, Sander M.J., Linderoth, Bengt, Joosten, Elbert A., Maino, Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6930820/
https://ncbi.nlm.nih.gov/pubmed/31334605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.13192
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