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Cell-mediated matrix stiffening accompanies capillary morphogenesis in ultra-soft amorphous hydrogels

There is a critical need for biomaterials that support robust neovascularization for a wide-range of clinical applications. Here we report how cells alter tissue-level mechanical properties during capillary morphogenesis using a model of endothelial-stromal cell co-culture within poly(ethylene glyco...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biomaterials
Hauptverfasser: Juliar, Benjamin A., Beamish, Jeffrey A., Busch, Megan E., Cleveland, David S., Nimmagadda, Likitha, Putnam, Andrew J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6930336/
https://ncbi.nlm.nih.gov/pubmed/31776019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2019.119634
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