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Deciphering the relative roles of matrix metalloproteinase- and plasmin-mediated matrix degradation during capillary morphogenesis using engineered hydrogels

Extracellular matrix (ECM) remodeling is essential for the process of capillary morphogenesis. Here we employed synthetic poly(ethylene glycol) (PEG) hydrogels engineered with proteolytic specificity to either matrix metalloproteinases (MMPs), plasmin, or both to investigate the relative contributio...

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Bibliografiska uppgifter
I publikationen:J Biomed Mater Res B Appl Biomater
Huvudupphovsmän: Beamish, Jeffrey A., Juliar, Benjamin A., Cleveland, David S., Busch, Megan E., Nimmagadda, Likitha, Putnam, Andrew J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2019
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6699943/
https://ncbi.nlm.nih.gov/pubmed/30784190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm.b.34341
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