IL-12 and Mucosal CD14(+) Monocyte-Like Cells Induce IL-8 in Colonic Memory CD4(+) T Cells of Patients With Ulcerative Colitis but not Crohn’s Disease

BACKGROUND AND AIMS: CD14(+) mononuclear phagocytes [MNPs] and T cells infiltrate colon in ulcerative colitis [UC]. Here we investigated how CD14(+) MNPs and the cytokines they produce shape the colonic effector T cell profile. METHODS: Colonic or mesenteric lymph node [mLNs] CD4(+) T cells isolated...

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Detalhes bibliográficos
Publicado no:J Crohns Colitis
Main Authors: Chapuy, Laurence, Bsat, Marwa, Rubio, Manuel, Sarkizova, Sisi, Therrien, Amélie, Bouin, Mickael, Orlicka, Katarzina, Weber, Audrey, Soucy, Geneviève, Villani, Alexandra-Chloé, Sarfati, Marika
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6930004/
https://ncbi.nlm.nih.gov/pubmed/31206576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ecco-jcc/jjz115
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