NFATc3-dependent expression of miR-153-3p promotes mitochondrial fragmentation in cardiac hypertrophy by impairing mitofusin-1 expression

Mitochondrial dysfunction is involved in the pathogenesis of various cardiovascular disorders. Although mitochondrial dynamics, including changes in mitochondrial fission and fusion, have been implicated in the development of cardiac hypertrophy, the underlying molecular mechanisms remain mostly unk...

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Udgivet i:Theranostics
Main Authors: Wang, Tao, Zhai, Mei, Xu, Sheng, Ponnusamy, Murugavel, Huang, Yan, Liu, Cui-Yun, Wang, Man, Shan, Chan, Shan, Pei-Pei, Gao, Xiang-Qian, Wang, Kai, Chen, Xin-Zhe, Liu, Jing, Xie, Jing-Yi, Zhang, De-Yu, Zhou, Lu-yu, Wang, Kun
Format: Artigo
Sprog:Inglês
Udgivet: Ivyspring International Publisher 2020
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6929994/
https://ncbi.nlm.nih.gov/pubmed/31903137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.37181
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