Targeting the STING pathway in tumor-associated macrophages regulates innate immune sensing of gastric cancer cells

Rationale:STING is a critical player in the innate and adaptive immune system, sensing cytosolic DNA to activate the expression of interferon genes and regulate T lymphocytes, which drives immunogenic responses to cancer cells. Tumor-associated macrophages (TAMs), abundantly present in the tumor mic...

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Udgivet i:Theranostics
Main Authors: Miao, Lei, Qi, Jingjing, Zhao, Qi, Wu, Qi-Nian, Wei, Da-Liang, Wei, Xiao-Li, Liu, Jia, Chen, Jun, Zeng, Zhao-Lei, Ju, Huai-Qiang, Luo, Hui-yan, Xu, Rui-Hua
Format: Artigo
Sprog:Inglês
Udgivet: Ivyspring International Publisher 2020
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6929973/
https://ncbi.nlm.nih.gov/pubmed/31903134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.37745
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