Long noncoding RNA PiHL regulates p53 protein stability through GRWD1/RPL11/MDM2 axis in colorectal cancer

We identified a novel long noncoding RNA (lncRNA) upregulated in colorectal cancer (CRC). We elucidated its role and clinical significance in CRC carcinogenesis. Methods: LncRNA candidates were identified using TCGA database. LncRNA expression profiles were studied by qRT-PCR and microarray in paire...

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Publicat a:Theranostics
Autors principals: Deng, Xuan, Li, Sihan, Kong, Fanyang, Ruan, Haoyu, Xu, Xiao, Zhang, Xinju, Wu, Zhiyuan, Zhang, Lin, Xu, Ying, Yuan, Hong, Peng, Haixia, Yang, Da, Guan, Ming
Format: Artigo
Idioma:Inglês
Publicat: Ivyspring International Publisher 2020
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6929633/
https://ncbi.nlm.nih.gov/pubmed/31903119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.36045
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