Mononuclear phagocyte system blockade improves therapeutic exosome delivery to the myocardium

Rationale: Exosomes are emerging as a promising drug delivery carrier. However, rapid uptake of exosomes by the mononuclear phagocyte system (MPS) remains an obstacle for drug delivery into other targeted organs, including the heart. We hypothesized that prior blocking of uptake of exosomes by the M...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Wan, Zhuo, Zhao, Lianbi, Lu, Fan, Gao, Xiaotong, Dong, Yan, Zhao, Yingxin, Wei, Mengying, Yang, Guodong, Xing, Changyang, Liu, Li
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6929612/
https://ncbi.nlm.nih.gov/pubmed/31903116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.38198
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