Mononuclear phagocyte system blockade improves therapeutic exosome delivery to the myocardium

Rationale: Exosomes are emerging as a promising drug delivery carrier. However, rapid uptake of exosomes by the mononuclear phagocyte system (MPS) remains an obstacle for drug delivery into other targeted organs, including the heart. We hypothesized that prior blocking of uptake of exosomes by the M...

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Dettagli Bibliografici
Pubblicato in:Theranostics
Autori principali: Wan, Zhuo, Zhao, Lianbi, Lu, Fan, Gao, Xiaotong, Dong, Yan, Zhao, Yingxin, Wei, Mengying, Yang, Guodong, Xing, Changyang, Liu, Li
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ivyspring International Publisher 2020
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6929612/
https://ncbi.nlm.nih.gov/pubmed/31903116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.38198
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