Microglia exacerbate white matter injury via complement C3/C3aR pathway after hypoperfusion

Microglial activation participates in white matter injury after cerebral hypoperfusion. However, the underlying mechanism is unclear. Here, we explore whether activated microglia aggravate white matter injury via complement C3-C3aR pathway after chronic cerebral hypoperfusion. Methods: Adult male Sp...

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Dades bibliogràfiques
Publicat a:Theranostics
Autors principals: Zhang, Lin-Yuan, Pan, Jiaji, Mamtilahun, Muyassar, Zhu, Yuan, Wang, Liping, Venkatesh, Ashwin, Shi, Rubing, Tu, Xuanqiang, Jin, Kunlin, Wang, Yongting, Zhang, Zhijun, Yang, Guo-Yuan
Format: Artigo
Idioma:Inglês
Publicat: Ivyspring International Publisher 2020
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6929610/
https://ncbi.nlm.nih.gov/pubmed/31903107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.35841
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