Fingolimod Inhibits Inflammation but Exacerbates Brain Edema in the Acute Phases of Cerebral Ischemia in Diabetic Mice

Background and Purpose: Diabetes mellitus increases stroke incidence and mortality and hampers functional recovery after stroke. Fingolimod has been shown to improve neurofunctional recovery and reduce brain infarction after ischemic injury in mice without comorbidities. In this work, we investigate...

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Vydáno v:Front Neurosci
Hlavní autoři: Li, Wanlu, He, Tingting, Jiang, Lu, Shi, Rubing, Song, Yaying, Mamtilahun, Muyassar, Ma, Yuanyuan, Zhang, Zhijun, Tang, Yaohui, Yang, Guo-Yuan, Wang, Yongting
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7432267/
https://ncbi.nlm.nih.gov/pubmed/32848587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2020.00842
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