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Identification of highly conserved, serotype-specific dengue virus sequences: implications for vaccine design

BACKGROUND: The sequence diversity of dengue virus (DENV) is one of the challenges in developing an effective vaccine against the virus. Highly conserved, serotype-specific (HCSS), immune-relevant DENV sequences are attractive candidates for vaccine design, and represent an alternative to the approa...

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Pubblicato in:BMC Genomics
Autori principali: Chong, Li Chuin, Khan, Asif M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6929274/
https://ncbi.nlm.nih.gov/pubmed/31874646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-019-6311-z
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