Oxidative Stress Increases Endogenous Complement-Dependent Inflammatory and Angiogenic Responses in Retinal Pigment Epithelial Cells Independently of Exogenous Complement Sources

Oxidative stress-induced damage of the retinal pigment epithelium (RPE) and chronic inflammation have been suggested as major contributors to a range of retinal diseases. Here, we examined the effects of oxidative stress on endogenous complement components and proinflammatory and angiogenic response...

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Veröffentlicht in:Antioxidants (Basel)
Hauptverfasser: Trakkides, Timon-Orest, Schäfer, Nicole, Reichenthaler, Maria, Kühn, Konstanze, Brandwijk, Ricardo J. M. G. E., Toonen, Erik J. M., Urban, Florian, Wegener, Joachim, Enzmann, Volker, Pauly, Diana
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6928869/
https://ncbi.nlm.nih.gov/pubmed/31766295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox8110548
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