Molecular switching from ubiquitin-proteasome to autophagy pathways in mice stroke model

The ubiquitin-proteasome system (UPS) and autophagy are two major pathways to degrade misfolded proteins that accumulate under pathological conditions. When UPS is overloaded, the degeneration pathway may switch to autophagy to remove excessive misfolded proteins. However, it is still unclear whethe...

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Vydáno v:J Cereb Blood Flow Metab
Hlavní autoři: Liu, Xia, Yamashita, Toru, Shang, Jingwei, Shi, Xiaowen, Morihara, Ryuta, Huang, Yong, Sato, Kota, Takemoto, Mami, Hishikawa, Nozomi, Ohta, Yasuyuki, Abe, Koji
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE Publications 2018
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6928553/
https://ncbi.nlm.nih.gov/pubmed/30375939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X18810617
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