Llwytho...

In vivo direct reprogramming of glial linage to mature neurons after cerebral ischemia

The therapeutic effect of in vivo direct reprogramming on ischemic stroke has not been evaluated. In the present study, a retroviral solution (1.5–2.0 × 10(7) /ul) of mock pMX-GFP (n = 13) or pMX-Ascl1/Sox2/NeuroD1 (ASN) (n = 14) was directly injected into the ipsilateral striatum and cortex 3 days...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Yamashita, Toru, Shang, Jingwei, Nakano, Yumiko, Morihara, Ryuta, Sato, Kota, Takemoto, Mami, Hishikawa, Nozomi, Ohta, Yasuyuki, Abe, Koji
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6662847/
https://ncbi.nlm.nih.gov/pubmed/31358888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47482-0
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