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Rapid zero-trans kinetics of Cs(+) exchange in human erythrocytes quantified by dissolution hyperpolarized (133)Cs(+) NMR spectroscopy

Transmembrane flux of Cs(+) (a K(+) congener) was measured in human red blood cells (RBCs; erythrocytes) on the 10-s time scale. This is the first report on dissolution dynamic nuclear polarization (dDNP) nuclear magnetic resonance (NMR) spectroscopy with this nuclide in mammalian cells. Four techni...

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Publicado en:Sci Rep
Main Authors: Kuchel, Philip W., Karlsson, Magnus, Lerche, Mathilde Hauge, Shishmarev, Dmitry, Ardenkjaer-Larsen, Jan Henrik
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6928147/
https://ncbi.nlm.nih.gov/pubmed/31873230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-56250-z
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