Sensing of nutrients by CPT1C regulates late endosome/lysosome anterograde transport and axon growth

Anterograde transport of late endosomes or lysosomes (LE/Lys) is crucial for proper axon growth. However, the role of energetic nutrients has been poorly explored. Malonyl-CoA is a precursor of fatty acids, and its intracellular levels highly fluctuate depending on glucose availability or the energy...

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Bibliografske podrobnosti
izdano v:eLife
Main Authors: Palomo-Guerrero, Marta, Fadó, Rut, Casas, Maria, Pérez-Montero, Marta, Baena, Miguel, Helmer, Patrick O, Domínguez, José Luis, Roig, Aina, Serra, Dolors, Hayen, Heiko, Stenmark, Harald, Raiborg, Camilla, Casals, Núria
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2019
Teme:
Cell Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6927751/
https://ncbi.nlm.nih.gov/pubmed/31868590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.51063
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