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Aberrant activation of cyclin A-CDK induces G2/M-phase checkpoint in human cells
Cyclin A-cyclin dependent kinase (CDK) activity is regulated by cyclin A proteolysis and CDK inhibitors (CKIs) during M and G1 phases. Our previous work has shown that constitutive activation of cyclin A-CDK in mouse somatic cells, by ectopic expression of stabilized human cyclin A2 (lacking the des...
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| Publicat a: | Cell Cycle |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6927705/ https://ncbi.nlm.nih.gov/pubmed/31760882 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2019.1693119 |
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