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Neutrophils remain detrimentally active in hydroxyurea-treated patients with sickle cell disease

Neutrophilia is a feature of sickle cell disease (SCD) that has been consistently correlated with clinical severity and has been shown to remain highly activated even at steady state. In addition to induction of fetal hemoglobin (HbF), hydroxyurea (HU) leads to reduction in neutrophil count and thei...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Barbu, Emilia Alina, Dominical, Venina M., Mendelsohn, Laurel, Thein, Swee Lay
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6927657/
https://ncbi.nlm.nih.gov/pubmed/31869367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0226583
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