Undetectable gadolinium brain retention in individuals with an age-dependent blood-brain barrier breakdown in the hippocampus and mild cognitive impairment

INTRODUCTION: Blood-brain barrier (BBB) breakdown is an early independent biomarker of human cognitive dysfunction, as found using gadolinium (Gd) as a contrast agent. Whether Gd accumulates in brains of individuals with an age-dependent BBB breakdown and/or mild cognitive impairment remains unclear...

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Bibliografski detalji
Izdano u:Alzheimers Dement
Glavni autori: Montagne, Axel, Huuskonen, Mikko T., Rajagopal, Gautham, Sweeney, Melanie D., Nation, Daniel A., Sepehrband, Farshid, D’Orazio, Lina M., Harrington, Michael G., Chui, Helena C., Law, Meng, Toga, Arthur W., Zlokovic, Berislav V.
Format: Artigo
Jezik:Inglês
Izdano: 2019
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6927478/
https://ncbi.nlm.nih.gov/pubmed/31862169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2019.07.012
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