Rainbow Trout IgM(+) B Cells Preferentially Respond to Thymus-Independent Antigens but Are Activated by CD40L

In the absence of class switch recombination and germinal centers, the mechanisms through which B cells from teleost fish mount extrafollicular immunoglobulin M (IgM) memory responses remains mostly unexplored. In this report, we demonstrate that teleost IgM(+) B cells respond to CD40L, a thymus-dep...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Granja, Aitor G., Perdiguero, Pedro, Martín-Martín, Alba, Díaz-Rosales, Patricia, Soleto, Irene, Tafalla, Carolina
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6927014/
https://ncbi.nlm.nih.gov/pubmed/31921163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02902
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