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CpG Oligodeoxynucleotides Modulate Innate and Adaptive Functions of IgM(+) B Cells in Rainbow Trout

Oligodeoxynucleotides (ODN) containing unmethylated CpG motifs have been widely postulated as vaccine adjuvants both in mammals and teleost fish. However, to date, the effects that CpGs provoke on cells of the adaptive immune system remain mostly unexplored in fish. Given that rainbow trout (Oncorhy...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Simón, Rocío, Díaz-Rosales, Patricia, Morel, Esther, Martín, Diana, Granja, Aitor G., Tafalla, Carolina
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6443966/
https://ncbi.nlm.nih.gov/pubmed/30972075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00584
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