Hydrophobically Modified let-7b miRNA Enhances Biodistribution to NSCLC and Downregulates HMGA2 In Vivo

MicroRNAs (miRNAs) have increasingly been shown to be involved in human cancer, and interest has grown about the potential use of miRNAs for cancer therapy. miRNA levels are known to be altered in cancer cells, including in non-small cell lung cancer (NSCLC), a subtype of lung cancer that is the mos...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Segal, Meirav, Biscans, Annabelle, Gilles, Maud-Emmanuelle, Anastasiadou, Eleni, De Luca, Roberto, Lim, Jihoon, Khvorova, Anastasia, Slack, Frank J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6926262/
https://ncbi.nlm.nih.gov/pubmed/31855835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2019.11.008
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