B cell receptor ligation induces display of V-region peptides on MHC class II molecules to T cells

The B cell receptors (BCRs) for antigen express variable (V) regions that are enormously diverse, thus serving as markers on individual B cells. V region-derived idiotypic (Id) peptides can be displayed as pId:MHCII complexes on B cells for recognition by CD4(+) T cells. It is not known if naive B c...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Huszthy, Peter Csaba, Gopalakrishnan, Ramakrishna Prabhu, Jacobsen, Johanne Tracey, Haabeth, Ole Audun Werner, Løset, Geir Åge, Braathen, Ranveig, Schenck, Karl, Tveita, Anders Aune, Munthe, Ludvig Andre, Bogen, Bjarne
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
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PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6926052/
https://ncbi.nlm.nih.gov/pubmed/31796587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1902836116
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