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Mechanisms of noncanonical binding dynamics in multivalent protein–protein interactions

Protein multivalency can provide increased affinity and specificity relative to monovalent counterparts, but these emergent biochemical properties and their mechanistic underpinnings are difficult to predict as a function of the biophysical properties of the multivalent binding partners. Here, we pr...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Errington, Wesley J., Bruncsics, Bence, Sarkar, Casim A.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6926015/
https://ncbi.nlm.nih.gov/pubmed/31776263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1902909116
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