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Mechanisms of noncanonical binding dynamics in multivalent protein–protein interactions

Protein multivalency can provide increased affinity and specificity relative to monovalent counterparts, but these emergent biochemical properties and their mechanistic underpinnings are difficult to predict as a function of the biophysical properties of the multivalent binding partners. Here, we pr...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Errington, Wesley J., Bruncsics, Bence, Sarkar, Casim A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6926015/
https://ncbi.nlm.nih.gov/pubmed/31776263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1902909116
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