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Mechanisms of noncanonical binding dynamics in multivalent protein–protein interactions

Protein multivalency can provide increased affinity and specificity relative to monovalent counterparts, but these emergent biochemical properties and their mechanistic underpinnings are difficult to predict as a function of the biophysical properties of the multivalent binding partners. Here, we pr...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Errington, Wesley J., Bruncsics, Bence, Sarkar, Casim A.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6926015/
https://ncbi.nlm.nih.gov/pubmed/31776263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1902909116
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