Heatstroke-induced hepatocyte exosomes promote liver injury by activating the NOD-like receptor signaling pathway in mice

BACKGROUND: Liver injury is a common and important clinical issue of severe heat stress (HS), which has toxic effects and promotes subsequent multiple organ failure. The pathogenesis of HS-induced liver injury has not been fully elucidated. Passively injured hepatocytes also drive liver injury. Exos...

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Udgivet i:PeerJ
Main Authors: Li, Yue, Zhu, Xintao, Zhang, Ming, Tong, Huasheng, Su, Lei
Format: Artigo
Sprog:Inglês
Udgivet: PeerJ Inc. 2019
Fag:
Emergency and Critical Care
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6925953/
https://ncbi.nlm.nih.gov/pubmed/31875151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.8216
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