Exendin-4 Protects against Hyperglycemia-Induced Cardiomyocyte Pyroptosis via the AMPK-TXNIP Pathway

Diabetic cardiomyopathy is a common cardiac condition in patients with diabetes mellitus, which results in cardiac hypertrophy and subsequent heart failure. Chronic inflammation in the diabetic heart results in loss of cardiomyocytes and subsequentially cardiac dysfunction. Accumulated evidence impl...

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Vydáno v:J Diabetes Res
Hlavní autoři: Wei, Hong, Bu, Rui, Yang, Qinghui, Jia, Jing, Li, Tao, Wang, Qiuping, Chen, Yanjun
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6925927/
https://ncbi.nlm.nih.gov/pubmed/31886288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/8905917
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