Metformin protects against myocardial ischemia-reperfusion injury and cell pyroptosis via AMPK/NLRP3 inflammasome pathway

Ischemia/reperfusion (I/R) injury is a life-threatening vascular emergency following myocardial infarction. Our previous study showed cardioprotective effects of metformin against myocardial I/R injury. In this study, we further examined the involvement of AMPK mediated activation of NLRP3 inflammas...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Zhang, Jing, Huang, Lelin, Shi, Xing, Yang, Liu, Hua, Fuzhou, Ma, Jianyong, Zhu, Wengen, Liu, Xiao, Xuan, Rui, Shen, Yunfeng, Liu, Jianping, Lai, Xiaoyang, Yu, Peng
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7762510/
https://ncbi.nlm.nih.gov/pubmed/33232283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.202143
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