SBF-1 inhibits contact hypersensitivity in mice through down-regulation of T-cell-mediated responses

BACKGROUND: T lymphocytes play an important role in contact hypersensitivity. This study aims to explore the immunosuppressive activity of SBF-1, an analog of saponin OSW-1, against T lymphocytes in vitro and in vivo. METHODS: Proliferation of T lymphocytes from lymph nodes of mice was determined by...

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Bibliographic Details
Published in:BMC Pharmacol Toxicol
Main Authors: Chen, Wei, Fang, Xianying, Gao, Yuan, Shi, Ke, Sun, Lijun, Yu, Biao, Luo, Qiong, Xu, Qiang
Format: Artigo
Language:Inglês
Published: BioMed Central 2019
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6925477/
https://ncbi.nlm.nih.gov/pubmed/31864413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40360-019-0377-8
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