Genomic risk score offers predictive performance comparable to clinical risk factors for ischaemic stroke

Recent genome-wide association studies in stroke have enabled the generation of genomic risk scores (GRS) but their predictive power has been modest compared to established stroke risk factors. Here, using a meta-scoring approach, we develop a metaGRS for ischaemic stroke (IS) and analyse this score...

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Pubblicato in:Nat Commun
Autori principali: Abraham, Gad, Malik, Rainer, Yonova-Doing, Ekaterina, Salim, Agus, Wang, Tingting, Danesh, John, Butterworth, Adam S., Howson, Joanna M. M., Inouye, Michael, Dichgans, Martin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6925280/
https://ncbi.nlm.nih.gov/pubmed/31862893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13848-1
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