Prolactin and its receptor as therapeutic targets in glioblastoma multiforme

Although prolactin (PRL) and its receptor (PRLR) have been detected in glioblastoma multiforme (GBM), their role in its pathogenesis remains unclear. Our aim was to explore their contribution in GBM pathogenesis. We detected PRL and PRLR in all GBM cell lines tested. PRLR activation or overexpressio...

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Udgivet i:Sci Rep
Main Authors: Asad, Antonela Sofía, Nicola Candia, Alejandro Javier, Gonzalez, Nazareno, Zuccato, Camila Florencia, Abt, Araceli, Orrillo, Santiago Jordi, Lastra, Yael, De Simone, Emilio, Boutillon, Florence, Goffin, Vincent, Seilicovich, Adriana, Pisera, Daniel Alberto, Ferraris, María Jimena, Candolfi, Marianela
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6925187/
https://ncbi.nlm.nih.gov/pubmed/31862900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-55860-x
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