Antiapoptotic Factor Humanin Is Expressed in Normal and Tumoral Pituitary Cells and Protects Them from TNF-α-Induced Apoptosis

Humanin (HN) is a 24-amino acid peptide with cytoprotective action in several cell types such as neurons and testicular germ cells. Rattin (HNr), a homologous peptide of HN expressed in several adult rat tissues, also has antiapoptotic action. In the present work, we demonstrated by immunocytochemic...

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Main Authors: Gottardo, María Florencia, Jaita, Gabriela, Magri, María Laura, Zárate, Sandra, Moreno Ayala, Mariela, Ferraris, Jimena, Eijo, Guadalupe, Pisera, Daniel, Candolfi, Marianela, Seilicovich, Adriana
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4216097/
https://ncbi.nlm.nih.gov/pubmed/25360890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0111548
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