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JNK-mediated Slit-Robo signaling facilitates epithelial wound repair by extruding dying cells

Multicellular organisms repair injured epithelium by evolutionarily conserved biological processes including activation of c-Jun N-terminal kinase (JNK) signaling. Here, we show in Drosophila imaginal epithelium that physical injury leads to the emergence of dying cells, which are extruded from the...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Iida, Chiaki, Ohsawa, Shizue, Taniguchi, Kiichiro, Yamamoto, Masatoshi, Morata, Ginés, Igaki, Tatsushi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6925126/
https://ncbi.nlm.nih.gov/pubmed/31863086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-56137-z
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