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Fusogenic liposomes effectively deliver resveratrol to the cerebral microcirculation and improve endothelium-dependent neurovascular coupling responses in aged mice

Adjustment of cerebral blood flow (CBF) to the increased oxygen and nutrient demands of active brain regions via neurovascular coupling (NVC) has an essential role in maintenance of healthy cognitive function. In advanced age, cerebromicrovascular oxidative stress and endothelial dysfunction impair...

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Publicat a:GeroScience
Autors principals: Wiedenhoeft, Tabea, Tarantini, Stefano, Nyúl-Tóth, Ádám, Yabluchanskiy, Andriy, Csipo, Tamas, Balasubramanian, Priya, Lipecz, Agnes, Kiss, Tamas, Csiszar, Anna, Csiszar, Agnes, Ungvari, Zoltan
Format: Artigo
Idioma:Inglês
Publicat: Springer International Publishing 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6925096/
https://ncbi.nlm.nih.gov/pubmed/31654270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-019-00102-1
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