Helicase Lymphoid-Specific Enzyme Contributes to the Maintenance of Methylation of SST1 Pericentromeric Repeats That Are Frequently Demethylated in Colon Cancer and Associate with Genomic Damage

DNA hypomethylation at repetitive elements accounts for the genome-wide DNA hypomethylation common in cancer, including colorectal cancer (CRC). We identified a pericentromeric repeat element called SST1 frequently hypomethylated (>5% demethylation compared with matched normal tissue) in several...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Epigenomes
Main Authors: Samuelsson, Johanna K., Dumbovic, Gabrijela, Polo, Cristian, Moreta, Cristina, Alibés, Andreu, Ruiz-Larroya, Tatiana, Giménez-Bonafé, Pepita, Alonso, Sergio, Forcales, Sonia-V., Manuel, Perucho
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6924650/
https://ncbi.nlm.nih.gov/pubmed/31867127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/epigenomes1010002
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados