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A novel long non-coding RNA from NBL2 pericentromeric macrosatellite forms a perinucleolar aggregate structure in colon cancer

Primate-specific NBL2 macrosatellite is hypomethylated in several types of tumors, yet the consequences of this DNA hypomethylation remain unknown. We show that NBL2 conserved repeats are close to the centromeres of most acrocentric chromosomes. NBL2 associates with the perinucleolar region and unde...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Dumbović, Gabrijela, Biayna, Josep, Banús, Jordi, Samuelsson, Johanna, Roth, Anna, Diederichs, Sven, Alonso, Sergio, Buschbeck, Marcus, Perucho, Manuel, Forcales, Sonia-V
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6009586/
https://ncbi.nlm.nih.gov/pubmed/29912433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky263
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