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DeepShape: estimating isoform-level ribosome abundance and distribution with Ribo-seq data

BACKGROUND: Ribosome profiling brings insight to the process of translation. A basic step in profile construction at transcript level is to map Ribo-seq data to transcripts, and then assign a huge number of multiple-mapped reads to similar isoforms. Existing methods either discard the multiple mappe...

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Bibliografske podrobnosti
izdano v:BMC Bioinformatics
Main Authors: Cui, Hongfei, Hu, Hailin, Zeng, Jianyang, Chen, Ting
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6923924/
https://ncbi.nlm.nih.gov/pubmed/31861979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-019-3244-0
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