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DeepShape: estimating isoform-level ribosome abundance and distribution with Ribo-seq data
BACKGROUND: Ribosome profiling brings insight to the process of translation. A basic step in profile construction at transcript level is to map Ribo-seq data to transcripts, and then assign a huge number of multiple-mapped reads to similar isoforms. Existing methods either discard the multiple mappe...
Enregistré dans:
| Publié dans: | BMC Bioinformatics |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6923924/ https://ncbi.nlm.nih.gov/pubmed/31861979 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-019-3244-0 |
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