Fluoride reactivation-enabled sensitive quantification of tabun adducts on human serum albumin by GC–MS/MS via isotope dilution

Organophosphorus nerve agents inhibit the cholinesterase activity by phosphylation of the active site serine. The resulting phosphylated cholinesterase and adducts on human serum albumin (HSA) are appropriate biomarkers for nerve agents exposure. Several methods have been developed for the detection...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Bioanalysis
Hauptverfasser: Li, Xiao-Sen, Wu, Ji-Na, Yan, Long, Xing, Zhong-Fang, Liu, Chang-Cai, Chen, Bo, Yuan, Ling, Yang, Yang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Newlands Press Ltd 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6923783/
https://ncbi.nlm.nih.gov/pubmed/31729243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/bio-2019-0161
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