Natriuretic peptide receptor C contributes to disproportionate right ventricular hypertrophy in a rodent model of obesity-induced heart failure with preserved ejection fraction with pulmonary hypertension

Heart failure with preserved ejection fraction (HFpEF) currently has no therapies that improve mortality. Right ventricular dysfunction and pulmonary hypertension are common in HFpEF, and thought to be driven by obesity and metabolic syndrome. Thus, we hypothesized that an animal model of obesity-in...

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Veröffentlicht in:Pulm Circ
Hauptverfasser: Agrawal, Vineet, Fortune, Niki, Yu, Sheeline, Fuentes, Julio, Shi, Fubiao, Nichols, David, Gleaves, Linda, Poovey, Emily, Wang, Thomas J., Brittain, Evan L., Collins, Sheila, West, James D., Hemnes, Anna R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: SAGE Publications 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6923530/
https://ncbi.nlm.nih.gov/pubmed/31903184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2045894019895452
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