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Adverse physiologic effects of Western diet on right ventricular structure and function: role of lipid accumulation and metabolic therapy

Little is known about the impact of metabolic syndrome (MS) on right ventricular (RV) structure and function. We hypothesized that mice fed a Western diet (WD) would develop RV lipid accumulation and impaired RV function, which would be ameliorated with metformin. Male C57/Bl6 mice were fed a WD or...

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Bibliografiske detaljer
Udgivet i:Pulm Circ
Main Authors: Brittain, Evan L., Talati, Megha, Fortune, Niki, Agrawal, Vineet, Meoli, David F., West, James, Hemnes, Anna R.
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6295706/
https://ncbi.nlm.nih.gov/pubmed/30451070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2045894018817741
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