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Multi-functional genome-wide CRISPR system for high throughput genotype–phenotype mapping
Genome-scale engineering is an indispensable tool to understand genome functions due to our limited knowledge of cellular networks. Unfortunately, most existing methods for genome-wide genotype–phenotype mapping are limited to a single mode of genomic alteration, i.e. overexpression, repression, or...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6923430/ https://ncbi.nlm.nih.gov/pubmed/31857575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13621-4 |
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