Improvement of developmental competence of cloned male pig embryos by short hairpin ribonucleic acid (shRNA) vector-based but not small interfering RNA (siRNA)-mediated RNA interference (RNAi) of Xist expression

Xist is an X-linked ribonucleic acid (RNA) gene responsible for the cis induction of X chromosome inactivation (XCI). In cloned mammalian embryos, Xist is ectopically activated at the morula to blastocyst stage on the X chromosome that is supposed to be active, thus resulting in abnormal XCI. Suppre...

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Detalhes bibliográficos
Publicado no:J Reprod Dev
Main Authors: YANG, Xuqiong, WU, Xiao, YANG, Yang, GU, Ting, HONG, Linjun, ZHENG, Enqin, XU, Zheng, ZENG, Fang, SHI, Junsong, ZHOU, Rong, CAI, Gengyuan, WU, Zhenfang, LI, Zicong
Formato: Artigo
Idioma:Inglês
Publicado em: The Society for Reproduction and Development 2019
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6923154/
https://ncbi.nlm.nih.gov/pubmed/31631092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1262/jrd.2019-070
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