Selective Engagement of FcγRIV by a M2e-Specific Single Domain Antibody Construct Protects Against Influenza A Virus Infection

Lower respiratory tract infections, such as infections caused by influenza A viruses, are a constant threat for public health. Antivirals are indispensable to control disease caused by epidemic as well as pandemic influenza A. We developed a novel anti-influenza A virus approach based on an engineer...

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Publicado en:Front Immunol
Autores principales: De Vlieger, Dorien, Hoffmann, Katja, Van Molle, Inge, Nerinckx, Wim, Van Hoecke, Lien, Ballegeer, Marlies, Creytens, Sarah, Remaut, Han, Hengel, Hartmut, Schepens, Bert, Saelens, Xavier
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6921966/
https://ncbi.nlm.nih.gov/pubmed/31921179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02920
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