Pro-inflammatory monocyte profile in patients with major depressive disorder and suicide behaviour and how ketamine induces anti-inflammatory M2 macrophages by NMDAR and mTOR

BACKGROUND: Depression is a highly prevalent disorder that is one of the leading causes of disability worldwide. Despite an unknown aetiology, evidence suggests that the innate and adaptive immune systems play a significant role in the development and maintenance of major depressive disorder (MDD)....

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Bibliografiske detaljer
Udgivet i:EBioMedicine
Main Authors: Nowak, Wanda, Grendas, Leandro Nicolás, Sanmarco, Liliana María, Estecho, Ivana Gisele, Arena, Ángeles Romina, Eberhardt, Natalia, Rodante, Demián Emanuel, Aoki, María Pilar, Daray, Federico Manuel, Carrera Silva, Eugenio Antonio, Errasti, Andrea Emilse
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2019
Fag:
Research paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6921226/
https://ncbi.nlm.nih.gov/pubmed/31753725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.10.063
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