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Green synthesis and biological evaluation of novel 5-fluorouracil derivatives as potent anticancer agents

This study reports the formation of 5-FU co-crystals with four different pharmacologically safe co-formers; Urea, Thiourea, Acetanilide and Aspirin using methanol as a solvent. Two fabrication schemes were followed i.e., solid-state grinding protocol, in which API and co-formers were mixed through v...

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Detalhes bibliográficos
Publicado no:Saudi Pharm J
Main Authors: Jubeen, Farhat, Liaqat, Aisha, Sultan, Misbah, Zafar Iqbal, Sania, Sajid, Imran, Sher, Farooq
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6921177/
https://ncbi.nlm.nih.gov/pubmed/31885476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsps.2019.09.013
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