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Evaluation of Skin Permeation and Retention of Topical Dapsone in Murine Cutaneous Leishmaniasis Lesions

The oral administration of dapsone (DAP) for the treatment of cutaneous leishmaniasis (CL) is effective, although serious hematological side effects limit its use. In this study, we evaluated this drug for the topical treatment of CL. As efficacy depends on potency and skin penetration, we first det...

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Foilsithe in:Pharmaceutics
Main Authors: Moreno, Esther, Calvo, Alba, Schwartz, Juana, Navarro-Blasco, Iñigo, González-Peñas, Elena, Sanmartín, Carmen, Irache, Juan Manuel, Espuelas, Socorro
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6920985/
https://ncbi.nlm.nih.gov/pubmed/31766282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics11110607
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